1. Cancer Gene Discovery: Past and Present

Christopher R. Clark, Wilaiwan DuRose, and Timothy K. Starr

Part I: Cancer Gene discovery In Silico based on Sequencing Data

1. Identification of Cancer Driver Genes from a Custom Set of Next Generation Sequencing Data

Shu-Hsuan Liu and Wei-Chung Cheng

1. Cancer Gene Discovery by Network Analysis of Somatic Mutations using the MUFFINN Server

Heonjong Han, Ben Lehner, and Insuk Lee

1. Identifying Driver Interfaces Enriched for Somatic Missense Mutations in Tumors

Kivilcim Ozturk and Hannah Carter

1. Identification of Cancer Genes Based on de novo Transposon Insertion Site Analysis using RNA and DNA Sequencing

Aaron Sarver

PartII: Cancer Gene Discovery using Cell and Organoid Systems

1. A Cell-based Method for Identification of Chemotherapy Resistance Cancer Genes

Raffaele Hellweg, Ashley Mooneyham, and Martina Bazzaro

1. Engineering a Bioartificial Human Colon Model through Decellularization and Recellularization

Huanhuan Joyce Chen and Michael L. Shuler

1. Mutagenesis Screens for Prostate Cancer using Replication-Incompetent Lentiviral Vectors

Grant D. Trobridge

1. Arrayed shRNA Screening to Identify Suppressors of Anchorage-independent Growth

Ugur Eskiocak

1. Genome-wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines

Charles H. Adelmann, Tim Wang, David M. Sabatini, and Eric S. Lander

1. CRISPR/Cas9 Based Positive Screens for Cancer Related Traits

Nicholas J. Slipek, Jyotika Varshney, and David A. Largaespada

1. Ex vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery

Kathryn A. O'Donnell, Yabin Guo, Shruthy Suresh, Barrett L. Updegraff, and Xiaorong Zhou

Part III: Cancer Gene Discovery using Animal Models

1. Cancer Gene Discovery Utilizing Sleeping Beauty Transposon Mutagenesis

Kelsie L. Becklin, Branden A. Smeester, and Branden S. Moriarity

1. PiggyBac Transposon-based Insertional Mutagenesis in Mice

Mathias J. Friedrich, Iraad F. Bronner, Pentao Liu, Allan Bradley, and Roland Rad

1. Liver-specific Delivery of Sleeping Beauty Transposon System by Hydrodynamic Injection for Cancer Gene Validation

Amy P. Chiu and Vincent W. Keng

1. Engineering Large Genomic Rearrangement in Mouse Embryonic Stem Cell for Cancer Gene Discovery

Yuen-Yi Tseng and Anindya Bagchi