SECTION 1: HEART, ENDOMYOCARDIAL BIOPSY CONGENITAL/GENETIC 4 Endocardial Fibroelastosis Syndrome 6 Arrhythmogenic Cardiomyopathy 10 Fatty Acid Metabolic Disorders 12 Mitochondrial Myopathies 16 Muscular Dystrophies 20 Glycogen Storage Diseases 22 Fabry Disease, Heart 24 LAMP2 Mutation (Danon Disease) ACQUIRED 26 Amyloid Deposition, Heart 32 Hemochromatosis, Heart 36 Anthracycline Cardiotoxicity 38 Catecholamine Cardiomyopathy 40 Cocaine Cardiotoxicity INFLAMMATORY 42 Lymphocytic Myocarditis 46 Giant Cell Myocarditis 48 Eosinophilic (Loeffler) Myocarditis 52 Sarcoidosis, Heart 54 Acute Rheumatic Carditis 58 Eosinophilic Granulomatosis With Polyangiitis 60 Viral Myocarditis 62 Toxoplasmosis, Heart 64 Chagas Disease, Heart 68 Lyme Disease and Rickettsial Myocarditis 72 Lupus Erythematosus, Heart TRANSPLANT REJECTION 78 Acute Cellular Transplant Rejection, Heart 84 Antibody-Mediated Transplant Rejection, Heart 90 Quilty Lesions 94 Previous Biopsy Sites, Heart Transplant 96 Posttransplant Lymphoproliferative Disorder, Heart 98 Harvesting Injury/Acute Ischemia, Heart SECTION 2: HEART, RESECTION HEART EXPLANT 104 Hypertrophic Cardiomyopathy 108 Idiopathic Dilated Cardiomyopathy 112 Ischemic Heart Disease 116 Overview of Coronary Artery Stents 120 Cardiac Allograft Vasculopathy 126 Radiation Injury, Heart 128 Cardiac Conduction System Disease 136 Ventricular Assist Devices 140 Approach to Cardiomyopathy (Worksheet) 142 Approach to Cardiomyopathy Diagnosis SECTION 3: HEART, TUMORS BENIGN 150 Cardiac Myxoma 156 Papillary Fibroelastoma 160 Cardiac Rhabdomyoma 164 Cardiac Fibroma 168 Ectopic Tissues, Heart 170 Lipomatous Hypertrophy of the Atrial Septum MALIGNANT 172 Cardiac Lymphoma 174 Cardiac Angiosarcoma 178 Cardiac Sarcoma, Other 182 Cardiac Metastases SECTION 4: CARDIAC VALVES, NATIVE AORTIC 190 Unicommissural Aortic Valve 194 Bicuspid Aortic Valve 198 Senile Calcific Aortic Stenosis 200 Discrete Membranous Subaortic Stenosis MITRAL 202 Myxomatous Mitral Valve Disease 206 Rheumatic Heart Disease TRICUSPID 210 Carcinoid Heart Disease 214 Ebstein Anomaly PULMONARY 216 Congenital Pulmonary Stenosis ENDOCARDITIS 218 Endocarditis, Native Valve 222 Nonbacterial Thrombotic Endocarditis SECTION 5: CARDIAC VALVES PROSTHETIC 228 Leaflet Degeneration, Prosthetic Valves 232 Thrombosis of Prosthetic Valves 234 Endocarditis, Prosthetic Valve 240 Mechanical Heart Valve Prostheses: Modes of Failure 242 Catheter-Deployed Valve Therapies SECTION 6: PERICARDIUM INFLAMMATORY 248 Acute Pericarditis 252 Constrictive Pericarditis 254 Tuberculous Pericarditis TUMORS 256 Lymphoma, Pericardium 258 Metastatic Tumor, Pericardium 262 Mesothelioma, Pericardium 266 Mesothelial/Monocytic Incidental Cardiac Excrescence (MICE) SECTION 7: VASCULAR DISEASE ENDARTERECTOMY/ATHERECTOMY/THROM BECTOMY 270 Overview of Peripheral Vascular Specimens 276 Thromboembolus, Vascular THORACIC AORTA 280 Aortic Degenerative Diseases 288 Genetic Diseases of the Aorta 292 Noninfectious Aortitis 296 Takayasu Arteritis 300 Aortic Dissection 304 Aortic Coarctation ABDOMINAL AORTA 308 Aortic Atherosclerosis and Complications 314 Chronic Periaortitis and IgG4-Related Disease 316 Mycotic Aneurysm CORONARY ARTERIES 320 Atherosclerosis, Coronary 324 Coronary Artery Dissection 326 Kawasaki Disease TEMPORAL ARTERIES 332 Giant Cell/Temporal Arteritis Monica P. Revelo, MD, PhD PERIPHERAL VESSELS 336 Buerger Disease (Thromboangiitis Obliterans) 340 Fibromuscular Dysplasia 346 Segmental Arterial Mediolysis 348 Mönckeberg Medial Calcific Sclerosis 350 Behçet Disease 354 Infectious Vasculitis 360 Lymphocytic Venulitis 362 Varicosities sakriti opis