Preface; 1 Genomic insulators in transgenic animals, Lluís Montoliu et al; 2 The GERMAN MOUSE CLINIC - Running an open access platform, Martin Hrabé de Angelis et al.; 3 Nature & Nurture: impacts on mouse phenotypes & translational research, Cory Brayton; 4 X The informatics of high-throughput mouse phenotyping: EUMODIC and beyond, John M Hancock and Hilary Gates; 5 Experimental tumour models in mice, Ritva Heljasvaara and Taina Pihlajaniemi; 6 Exploration of MMP function in mouse models of angiogenesis, Agnès NOEL et al.; 7 Tumor- stroma interactions: focus on fibroblasts, Donald Gullberg and Rolf K. Reed; 8 Experimental procedures to assay invasion-associated activities of primary cultured fibroblasts, Olivier De Wever et al.; 9 Systemic Instigation: A Mouse Model to Study Breast Cancer as a Systemic Disease, Sandra S. McAllister; Index