- Tyrosine Phosphorylation in Cell Signaling: Discovery and Beyond - Protein Tyrosine Phosphatase Super-Family of Proteins - The PTP-Fold: Conserved Structure and Enzyme Mechanism -The Bi-Domain RPTPs - Modes of PTP Regulation Seen in Signaling - Role of PTPs in Metabolism: PTP1B as the Prototype - RPTPs in the Immune System: Special Role of CD45 - RPTPs in Axon Guidance - Approaches to Study PTPs in Live Cells - Role of PTPs in Host-Pathogen Interactions: Prokaryotic PTPs - PTP Inhibitors in Drug Discovery: Conservative Approaches and New Frontiers sakriti opis