Introduction.- Scope of Technical Diagnostics.- Application of Technical Diagnostics.- Physics of Failure.- Methods and Techniques for Diagnostics and Monitoring.- Overview of Diagnostics and Monitoring Methods and Techniques.- Stress and Strain Determination.- Modal Analysis.- Vibration Analysis.- Acoustic Emission.- Nondestructive Evaluation.- Infrared Thermography.- Industrial Radiology.- Computed Tomography.- Embedded Sensors.- Micro-Diagnostics: X-ray and Synchrotron Techniques.- Surface Chemical Analysis at the Micro and Nano Scale.- Subsurface Microstructural Analysis.- Technical Diagnostics of Machines and Plants.- Principles and Concepts of Technical Failure Analysis.- Failure Analysis: Case Studies.- Machinery Diagnostics.- Structural Health Monitoring and Performance Control.- Principles, Concepts and Assessment of Structural Health Monitoring.- Buildings.- Bridges.- Pipelines.- Electric Power Stations and Transmission Networks.- Offshore Wind Structures.- Railway Systems.- Guidelines for Structural Health Monitoring.- Excursion.- Diagnostics in Arts and Culture.