1 Recent International Efforts to Improve Bivalve Molluscan Shellfish Safety Iddya Karunasagar

Part I Management and Regulation/Gestion et la réglementation

2 Evolution of PSP Toxicity in Shellfish from the Beagle Channel (Tierra del Fuego, Argentina): An Overview
Alejandra Beatriz Goya and Santiago Maldonado

3 Storage and Detoxification of Bivalve Molluscs as a Tool in a Marketing Strategy
J. Haure, J. Hussenot, F. Buzin, Patrick Lassus, C. Marcaillou, F. Mondeguer, V. S echet, F. Royer, Zouher Amzil, M. Cardinal, L. Le Grel, A. Mass e, N.E. Sabiri, J.B. Castaing, and P. Jaouen

4 Molluscan Shellfish Safety in South America
Dinorah Medina, Alejandra Beatriz Goya, and Claudia Rozas

5 Mitigating the Impacts of Paralytic Shellfish Poisoning During Harmful Algal Bloom Episodes in the Philippines
Ulysses M. Montojo, Marc Lawrence J. Romero, Ronald Jefferson A. Narceda, and Noime S. Walican

6 New Zealand Aquaculture Industry Initiative: Collingwood Case Study
Helen Smale

7 Regulatory Perspective in Translating Science into Policy: Challenges in Utilizing Risk Assessment for the Elaboration of Codex Standards of Shellfish Safety
Hajime Toyofuku

8 Defining a Sampling Strategy for Okadaic Acid (OA) Toxins in Shellfish to Determine the Human Health Status of a Growing Area
Nathalie Wesolek, Franc ois-Gilles Carpentier, Dominique Parent-Massin, and Alain-Claude Roudot

Part II Health Risk Assessment/E valuation de risques a` la santé

9 Contribution of Shellfish Consumption to the Dietary Exposure of the French Population to Chemical Contaminants
Nathalie Arnich, V eronique Sirot, and Jean-Charles Leblanc

10 Probabilistic Exposure Assessment to Phycotoxins by Recreational Shellfish Harvesters: Results and Influence of Shellfish Species and the Cooking Process
Cyndie Picot, G. Limon, G. Durand, Dominique Parent-Massin, and Alain-Claude Roudot

11 Vibrio parahaemolyticus Risk Management in Japan
Hajime Toyofuku

12 Distribution of Cd, Pb, As and Hg in Oyster Tissue, Sediment andWater in Lingayen Gulf, Philippines
Reivin T. Vinarao, Gielenny M. Salem, and Rosario J. Ragaza

Part III Enteric Viruses/Virus ent eriques

13 Proposed Draft Guidelines for the Application of General Principles of Food Hygiene to Control of Viruses in Food
Ingeborg L.A. Boxman

14 Bioaccumulation and Removal Dynamics of Murine Norovirus in Manila Clams ( Venerupis philippinarum ) and Mussels ( Mytilus galloprovincialis )
D. Polo, C. A lvarez, J. D iez, C.F. Manso, M. Angulo, M.L. Vilari no, S. Darriba, A. Longa, and J.L. Romalde

15 Detection of Enteric Viruses in Shellfish
Gary P. Richards, Dean O. Cliver, and Gail E. Greening

Part IV Chemical Analytical Methods/M ethodes d'analyse chimique

16 Searching for Internal Standard for Chemical Routine Analysis of Lipophilic Shellfish Toxins
Trude S. Guldberg, T. Hatlen, and K. Aarstad

17 Effect of Dilution Rate on Azadinium spinosum and Azaspiracid (AZA) Production in Pilot Scale

Photobioreactors for the Harvest of AZA1 and -2
T. Jauffrais, V. S echet, P. Truquet, Zouher Amzil, C. Herrenknecht, and P. Hess

18 A Comparison of Assay Techniques for the Analysis of Diarrhetic Shellfish Poisoning Toxins in Shellfish
R. Raine, A.M. Wilson, G. Hermann, and J.P. Lacaze

Part V Metabolism of Toxins in Molluscan Shellfish/M etabolisme des toxines dans les coquillages

19 Accumulation of Okadaic Acid and Detoxifying Enzymes in the Digestive Gland of Mytilus galloprovincialis During Exposure to DSP
A. Vidal, Y. Ruiz, P. Su arez, Ana Alonso Martinez, A.E. Rossignoli, J. Blanco, O. Garcia, and F. San Juan

Part VI Chemical Contaminants/Polluants chimiques

20 In Vitro Toxicity and Histopathological Effects Induced in the Mantle Tissue of Males of Mytilus galloprovincialis During Short-Term Exposure to a Tar Mixture
Ana Alonso Martinez, P. Su arez, Y. Ruiz, A. Vidal, and F. San Juan

21 Histopathological Alterations of the